THERAPEUTIC TARGETING OF ALTERNATIVE SPLICING

Gene transcription leads to the generation of pre-mRNA molecules which contain both coding sequences (exons) and intervening Classic Cap non-coding sequences (introns).The primary transcript needs further processing which involves the excision of introns and ligation of exons.This process is called RNA splicing.Nearly all primary transcripts underg

Introduction: Multi-view data offer advantages over single-view data for characterizing individuals, which is crucial in precision medicine toward personalized prevention, diagnosis, or treatment follow-up.Methods: Here, we develop a network-guided multi-view clustering framework named netMUG to identify actionable subgroups of individuals.This pip